PittsburghV1, Main, Exploration, bibRecord, 000387

Pentoxifylline attenuates leukocyte-endothelial interactions in a two-hit model of shock and sepsis.

Identifieur interne : 000387 ( Main/Exploration ); précédent : 000386; suivant : 000388

Pentoxifylline attenuates leukocyte-endothelial interactions in a two-hit model of shock and sepsis.

Auteurs : Naomi Kondo Nakagawa [Brésil] ; Ruy J. Cruz [États-Unis] ; Priscila Aikawa [Brésil] ; Cristiano J. Correia [Brésil] ; José Walber Miranda Costa Cruz [Brésil] ; Thais Mauad [Brésil] ; Haibo Zhang [Canada] ; Mauricio Rocha-E-Silva [Brésil] ; Paulina Sannomiya [Brésil]

Source :

The Journal of surgical research [ 1095-8673 ] ; 2015.

RBID : pubmed:25224275

Descripteurs français

KwdFr :
- Animaux, Caecum (traumatismes), Cellules endothéliales (), Choc hémorragique (immunologie), Choc hémorragique (traitement médicamenteux), Communication cellulaire (), Défaillance multiviscérale (immunologie), Défaillance multiviscérale (traitement médicamenteux), Ligature, Microcirculation (), Modèles animaux de maladie humaine, Molécule-1 d'adhérence intercellulaire (métabolisme), Mâle, Pentoxifylline (pharmacologie), Piégeurs de radicaux libres (pharmacologie), Plaies par arme blanche, Rat Wistar, Roulement des leucocytes (), Réanimation (), Sepsie (immunologie), Sepsie (traitement médicamenteux), Solution isotonique (pharmacologie), Sélectine P (métabolisme).
MESH :
- immunologie : Choc hémorragique, Défaillance multiviscérale, Sepsie.
- métabolisme : Molécule-1 d'adhérence intercellulaire, Sélectine P.
- pharmacologie : Pentoxifylline, Piégeurs de radicaux libres, Solution isotonique.
- traitement médicamenteux : Choc hémorragique, Défaillance multiviscérale, Sepsie.
- traumatismes : Caecum.
- Animaux, Cellules endothéliales, Communication cellulaire, Ligature, Microcirculation, Modèles animaux de maladie humaine, Mâle, Plaies par arme blanche, Rat Wistar, Roulement des leucocytes, Réanimation.

English descriptors

KwdEn :
- Animals, Cecum (injuries), Cell Communication (drug effects), Disease Models, Animal, Endothelial Cells (drug effects), Free Radical Scavengers (pharmacology), Intercellular Adhesion Molecule-1 (metabolism), Isotonic Solutions (pharmacology), Leukocyte Rolling (drug effects), Ligation, Male, Microcirculation (drug effects), Multiple Organ Failure (drug therapy), Multiple Organ Failure (immunology), P-Selectin (metabolism), Pentoxifylline (pharmacology), Rats, Wistar, Resuscitation (methods), Sepsis (drug therapy), Sepsis (immunology), Shock, Hemorrhagic (drug therapy), Shock, Hemorrhagic (immunology), Wounds, Stab.
MESH :
- chemical , metabolism : Intercellular Adhesion Molecule-1, P-Selectin.
- chemical , pharmacology : Free Radical Scavengers, Isotonic Solutions, Pentoxifylline.
- drug effects : Cell Communication, Endothelial Cells, Leukocyte Rolling, Microcirculation.
- drug therapy : Multiple Organ Failure, Sepsis, Shock, Hemorrhagic.
- immunology : Multiple Organ Failure, Sepsis, Shock, Hemorrhagic.
- injuries : Cecum.
- methods : Resuscitation.
- Animals, Disease Models, Animal, Ligation, Male, Rats, Wistar, Wounds, Stab.

Abstract

This study investigated the effects of pentoxifylline (PTX) combined with resuscitation fluids on microcirculatory dysfunctions in a two-hit model of shock and sepsis.

DOI: 10.1016/j.jss.2014.07.034
PubMed: 25224275

Affiliations:

Le document en format XML

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<term>Cell Communication (drug effects)</term>
<term>Disease Models, Animal</term>
<term>Endothelial Cells (drug effects)</term>
<term>Free Radical Scavengers (pharmacology)</term>
<term>Intercellular Adhesion Molecule-1 (metabolism)</term>
<term>Isotonic Solutions (pharmacology)</term>
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<term>Pentoxifylline</term>
</keywords>
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<term>Endothelial Cells</term>
<term>Leukocyte Rolling</term>
<term>Microcirculation</term>
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<term>Shock, Hemorrhagic</term>
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<term>Défaillance multiviscérale</term>
<term>Sepsie</term>
</keywords>
<keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Multiple Organ Failure</term>
<term>Sepsis</term>
<term>Shock, Hemorrhagic</term>
</keywords>
<keywords scheme="MESH" qualifier="injuries" xml:lang="en"><term>Cecum</term>
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<term>Sélectine P</term>
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<keywords scheme="MESH" qualifier="pharmacologie" xml:lang="fr"><term>Pentoxifylline</term>
<term>Piégeurs de radicaux libres</term>
<term>Solution isotonique</term>
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<term>Ligation</term>
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<term>Mâle</term>
<term>Plaies par arme blanche</term>
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<front><div type="abstract" xml:lang="en">This study investigated the effects of pentoxifylline (PTX) combined with resuscitation fluids on microcirculatory dysfunctions in a two-hit model of shock and sepsis.</div>
</front>
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<li>États-Unis</li>
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<li>Pennsylvanie</li>
<li>État de São Paulo</li>
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<li>Toronto</li>
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<orgName><li>Université de Toronto</li>
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<tree><country name="Brésil"><region name="État de São Paulo"><name sortKey="Nakagawa, Naomi Kondo" sort="Nakagawa, Naomi Kondo" uniqKey="Nakagawa N" first="Naomi Kondo" last="Nakagawa">Naomi Kondo Nakagawa</name>
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<name sortKey="Aikawa, Priscila" sort="Aikawa, Priscila" uniqKey="Aikawa P" first="Priscila" last="Aikawa">Priscila Aikawa</name>
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<name sortKey="Mauad, Thais" sort="Mauad, Thais" uniqKey="Mauad T" first="Thais" last="Mauad">Thais Mauad</name>
<name sortKey="Rocha E Silva, Mauricio" sort="Rocha E Silva, Mauricio" uniqKey="Rocha E Silva M" first="Mauricio" last="Rocha-E-Silva">Mauricio Rocha-E-Silva</name>
<name sortKey="Sannomiya, Paulina" sort="Sannomiya, Paulina" uniqKey="Sannomiya P" first="Paulina" last="Sannomiya">Paulina Sannomiya</name>
</country>
<country name="États-Unis"><region name="Pennsylvanie"><name sortKey="Cruz, Ruy J" sort="Cruz, Ruy J" uniqKey="Cruz R" first="Ruy J" last="Cruz">Ruy J. Cruz</name>
</region>
</country>
<country name="Canada"><region name="Ontario"><name sortKey="Zhang, Haibo" sort="Zhang, Haibo" uniqKey="Zhang H" first="Haibo" last="Zhang">Haibo Zhang</name>
</region>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Wicri/Amérique/explor/PittsburghV1/Data/Main/Exploration

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000387 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000387 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Wicri/Amérique
   |area=    PittsburghV1
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     pubmed:25224275
   |texte=   Pentoxifylline attenuates leukocyte-endothelial interactions in a two-hit model of shock and sepsis.
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i   -Sk "pubmed:25224275" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd   \
       | NlmPubMed2Wicri -a PittsburghV1

This area was generated with Dilib version V0.6.38.
Data generation: Fri Jun 18 17:37:45 2021. Site generation: Fri Jun 18 18:15:47 2021

Serveur d'exploration sur Pittsburgh

Pentoxifylline attenuates leukocyte-endothelial interactions in a two-hit model of shock and sepsis.

Pentoxifylline attenuates leukocyte-endothelial interactions in a two-hit model of shock and sepsis.

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki

	Serveur d'exploration sur Pittsburgh
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.